Volodymyr Lushchak: A life in science To the 70th anniversary of a biochemist, educator, and founder of a scientific school
DOI:
https://doi.org/10.15330/jpnubio.13.62-71Keywords:
Volodymyr Lushchak, Volodymyr I Lushchak, V Lushchak, biochemistAbstract
Born on September 18, 1956, in Stanislav (now Ivano-Frankivsk), Volodymyr Lushchak followed a rather unconventional route into science. Only after completing military service, he entered the Faculty of Biology at Moscow State University, the most prestigious center of biological research in the Soviet Union. Upon graduating in 1982, he continued his academic training as a doctoral student of Professor Alexander Boldyrev, whose group focused on membrane ion transport processes. Four years later, he earned his PhD with a dissertation entitled “The role of protein-protein and protein-lipid interactions in the functioning of the sarcoplasmic reticulum Ca pump.”
References
Balatskyi, V. A., Dmytriv, T. R., Divnych, A., & Lushchak, V. I. (2025). Kefir enhances stress resilience and mitigates PTSD-related behavioral and hematological changes in mice. Frontiers in Physiology, 16. https://doi.org/10.3389/fphys.2025.1682807
Balatskyi, V., Gospodaryov, D., Abrat, O., Strilbytska, O., Demianchuk, O., Tkachyk, A., Vasylyshyn, O., Lushchak, O., Lushchak, V. I., & Bayliak, M. (2025). Differential long-term effects of physical, social, and psychological stressors in male mice: Down-regulation of inflammatory markers and unresponsiveness of the antioxidant system. Physiology & Behavior, 115065. https://doi.org/10.1016/j.physbeh.2025.115065
Bayliak, M. M., Sorochynska, O. M., Kuzniak, O. V., Gospodaryov, D. V., Demianchuk, O. I., Vasylyk, Y. V., Mosiichuk, N. M., Storey, K. B., Garaschuk, O., & Lushchak, V. I. (2021). Middle age as a turning point in mouse cerebral cortex energy and redox metabolism: Modulation by every-other-day fasting. Experimental Gerontology, 145, 111182. https://doi.org/10.1016/j.exger.2020.111182
Demianchuk, O., Bayliak, M., Vatashchuk, M., Gospodaryov, D., Hurza, V., Derkachov, V., Berezovskyi, V., & Lushchak, V. I. (2025). Alpha-ketoglutarate promotes anxiety, activates autophagy, and suppresses antioxidant enzymes in the cerebral cortex of female mice on cafeteria diet. Brain Research Bulletin, 111255. https://doi.org/10.1016/j.brainresbull.2025.111255
Demianchuk, O., Vatashchuk, M., Gospodaryov, D., Hurza, V., Ivanochko, M., Derkachov, V., Berezovskyi, V., Lushchak, O., Storey, K. B., Bayliak, M., & Lushchak, V. I. (2024). High-fat high-fructose diet and alpha-ketoglutarate affect mouse behavior that is accompanied by changes in oxidative stress response and energy metabolism in the cerebral cortex. Biochimica et Biophysica Acta (BBA) - General Subjects, 1868(1), 130521. https://doi.org/10.1016/j.bbagen.2023.130521
Gospodaryov, D. V. (2022). Battlefields for research in Ukraine. Nature Aging. https://doi.org/10.1038/s43587-022-00221-z
Lushchak, O. V., Bahniukova, T. V., & Lushchak, V. I. (2003). Effect of aminotriazole on the activity of catalase and glucose-6-phosphate dehydrogenase in tissues of two frog species – Rana ridibunda and Rana esculenta. The Ukrainian Biochemical Journal, 75(4), 45–50.
Lushchak, O. V., Gospodaryov, D. V., Rovenko, B. M., Glovyak, A. D., Yurkevych, I. S., Klyuba, V. P., Shcherbij, M. V., & Lushchak, V. I. (2011). Balance between macronutrients affects life span and functional senescence in fruit fly Drosophila melanogaster. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 67A(2), 118–125. https://doi.org/10.1093/gerona/glr184
Lushchak, V. I. (2014). Free radicals, reactive oxygen species, oxidative stress and its classification. Chemico-Biological Interactions, 224, 164–175. https://doi.org/10.1016/j.cbi.2014.10.016
Lushchak, V. I. (2015). Free radicals, reactive oxygen species, oxidative stresses and their classifications. The Ukrainian Biochemical Journal, 87(6), 11–18. https://doi.org/10.15407/ubj87.06.011
Lushchak, V. I., Lushchak, L. P., Mota, A. A., & Hermes-Lima, M. (2001). Oxidative stress and antioxidant defenses in goldfish Carassius auratus during anoxia and reoxygenation. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 280(1), R100—R107. https://doi.org/10.1152/ajpregu.2001.280.1.r100
Lushchak, V. I., Murray, P., & Cossins, A. R. (2007). The effect of temperature increase on the expression of manganese superoxide dismutase in tissues of common carp Cyprinus carpio. The Ukrainian Biochemical Journal, 79(2), 87–91.
Lushchak, V., & Gospodaryov, D. (2005). Catalases protect cellular proteins from oxidative modification in. Cell Biology International, 29(3), 187–192. https://doi.org/10.1016/j.cellbi.2004.11.001
Rovenko, B. M., Kubrak, O. I., Gospodaryov, D. V., Perkhulyn, N. V., Yurkevych, I. S., Sanz, A., Lushchak, O. V., & Lushchak, V. I. (2015). High sucrose consumption promotes obesity whereas its low consumption induces oxidative stress in Drosophila melanogaster. Journal of Insect Physiology, 79, 42–54. https://doi.org/10.1016/j.jinsphys.2015.05.007
Semaniuk, U. V., Gospodaryov, D. V., Feden'ko, K. M., Yurkevych, I. S., Vaiserman, A. M., Storey, K. B., Simpson, S. J., & Lushchak, O. (2018). Insulin-Like peptides regulate feeding preference and metabolism in drosophila. Frontiers in Physiology, 9. https://doi.org/10.3389/fphys.2018.01083
Semchyshyn, H. M., & Lushchak, V. I. (2004). Oxidative stress and control of catalase activity in Escherichia coli. The Ukrainian Biochemical Journal, 76(2), 31–42. (in Ukrainian).
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Copyright (c) 2026 Maria Bailyak, Dmytro Gospodaryov, Oleksandra Abrat, Viktor Husak
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